भा.प्रौ.सं. गाँधीनगर: उत्कृषटता के 15 वर्षसमाचार
अनुसंधान

Ritu Varshney

  1. Senior Research Staff

  2. Ritu Varshney

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Ritu Varshney

Post-Doctoral Fellow, Biological Engineering

B.Sc.: Ch. Charan Singh University, Meerut, Uttar Pradesh
M.Sc.: Ch. Charan Singh University, Meerut, Uttar Pradesh
Ph.D.: Indian Institute of Technology Roorkee

Email: ritu.v -AT- iitgn.ac.in



  • Work experience

    • Post-Doctoral Fellow, Indian Institute of Technology, Gandhinagar (Present)
    • Post-Doctoral Fellow, Indian Institute of Technology, Roorkee in collaboration with Michigan Diagnostics USA (2018-2019)

  • Selected Publications

    1. Varshney, R., Gupta, S. and Roy, P., 2017. Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic β-cell death through modulation of autophagy via AMPK/mTOR signaling pathway. Molecular and cellular endocrinology, 448, pp.1-20.

    2. Varshney, R., Mishra, R., Gupta, S., Sircar, D. and Roy, P., 2018. Kaempferol alleviates palmitic acid-induced lipid stores, endoplasmic reticulum stress and pancreatic β-cell dysfunction through AMPK/mTOR-mediated lipophagy. The Journal of nutritional biochemistry, 57, pp.212-227.

    3. Varshney, R., Mishra, R. and Roy, P., 2019. A comparative analysis of various flavonoids in the regulation of obesity and diabetes: in vitro and in vivo study. Journal of functional foods 59, pp. 194-205.

    4. Rai, S., Singh, P., Varshney, R., Chaturvedi, V., Vamanue, E., Singh, M. P., Singh B. K., 2020. Promising drug targets and associated therapeutic interventions in Parkinson’s disease. Neural Regeneration Research 16(9):1730-1739. Equal first author

    5. Varshney, R., Das, N., Mishra, R. and Roy, P. Structure-function elucidation of flavonoids by modern technologies. CRC press, ISBN 9781138733060.

    6. Verma, P., Kar, B., Varshney, R., Roy, P. and Sharma, A.K., 2017. Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis. The FEBS journal, 284(24), pp.4233-4261.

    7. Saini, M., Masirkar, Y., Varshney, R., Roy, P. and Sadhu, K. K., 2017. Fluorogen-free aggregation induced NIR emission from gold nanoparticles. Chemical Communications, 53(46), pp. 6199-6202.

    8. Gupta, P., Agarwal, A., Kumaraswamy, M., Varshney, R., Beniwal, S., Manhas, S., Roy, P., Lahiri, D., 2019. Comparison of Neural Cell Adhesion and Neurite Outgrowth on Carbon Nanotube and Graphene Reinforced Chitosan Scaffolds. Materials Science & Engineering C, 97, pp. 539-551.

  • Awards

    1. Awarded prestigious DST-SERB-National Postdoctoral Fellowship 2020 as principal investigator for the project “Screening of natural flavonoids as the potential autophagy modulators in the regulation of diabetes-associated Alzheimer’s disease” from The Department of Science & Technology, Ministry of Science and Technology, Government of India (funding of 22,23,600 for 2 years).
    2. Awarded reputed DBT-RA 2020 fellowship for the project entitled “To Study the effects of autophagy modulators in alleviation of breast cancer metastasis” from Department of Biotechnology, Ministry of Science and Technology, Government of India (funding of 15,98,720 for 2 years)
    3. Qualified GATE 2013 for scholarship in Biotechnology.
    4. Qualified UP SLET 2012 (UP CET) for Ph.D. in Life science.
    5. Qualified GATE 2012 for scholarship in Life Science.
    6. Qualified UGC-JRF Dec 2011 for fellowship as well as lectureship in Life science.
    7. Qualified GATE 2011 for scholarship in Life Science.
    8. Qualified CSIR- UGC-NET Dec 2010 for lectureship in Life science.
    9. Received UGC-JRF as well as UGC-SRF fellowship during Ph.D.
    10. Selected for Institute’s (IIT Roorkee’s) fellowship twice based on performance and publications to carry out research during Ph.D.
    11. Got performance appraisal Prize & Certificate in class 10th and 12th.
    12. Won Prize & certificate in a state-level science competition organized by ‘Pioneer Pragati Parivar’in 2004.
    13. The research article entitled “Fluorogen-free Aggregation Induced NIR Emission from Gold Nanoparticles” has been highlighted on the inside back cover of the journal. Chem. Commun. 2017, 53, 6199.
    14. The research article entitled “Fluorogen-free Aggregation Induced NIR Emission from Gold Nanoparticles” has been indexed in NATURE INDEX.
    15. The research article entitled “Fluorogen-free Aggregation Induced NIR Emission from Gold Nanoparticles” was featured in chemistry views magazine.
    16. The research article entitled “Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic β-cell death through modulation of autophagy via AMPK/mTOR signaling pathway” was featured in pancreatic cell news (Volume 8.08, Feb 28) and “Better understanding through technology & emerging research” news.
    17. The research article entitled “Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic β-cell death through modulation of autophagy via AMPK/mTOR signaling pathway” has been the most downloaded and highly cited article of prestigious Molecular and Cellular Endocrinology Journal.
    18. The research article entitled “Kaempferol alleviates palmitic acid-induced lipid stores, endoplasmic reticulum stress and pancreatic β-cell dysfunction through AMPK/mTOR-mediated lipophagy” has been the most downloaded and highly cited article of prestigious The Journal of nutritional biochemistry.

Research Interests

  • ● Autophagy
  • ● Natural Products
  • ● Cancer Biology
  • ● Neurological Disorders
  • ● Metabolic Disorders