Sivapriya Kirubakaran
Sivapriya Kirubakaran
Kankuben Bakshirambhai Gelot Chair Associate Professor, Chemistry
- BSc: The Ethiraj college for women, 1999
- MSc: University of Madras, 2001
- PhD: IISc Bangalore, 2007
Email: priyak -AT- iitgn.ac.in
Website : http://labs.iitgn.ac.in/ccbl/
Office:
4/401 B
VOIP:
2450
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Selected Publications
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Juvale, K.*; Purushothaman, G.*; Singh, V.; Shaik, A.; Ravi, S.;Thiruvenkatam, V.; Kirubakaran, S., Identification of selective inhibitors of Helicobacter pylori IMPDH as a targeted therapy for the infectionScientific Reports, 2019 9:190. DOI: 10.1038/s41598-018-37490-x (* Equal first authors).
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Bhakuni, R.; Shaik, A.; Kirubakaran, S., Evaluation of MBP tagged-hATR kinase domain catalytic activity with p53 Ser-15 phosphorylation. Biochemistry, 2018, 57, 47, 6592-6603.
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Shaik, A.; Bhakuni, R.; Kirubakaran, S., Design, Synthesis, and Docking Studies of New Torin2 Analogs as Potential ATR/mTOR Kinase Inhibitors. Molecules 2018, 23 (5), 992.
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Bhoir, S.; Shaik, A.; Thiruvenkatam, V. *; Kirubakaran, S. *, High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer. Scientific Reports 2018, 8 (1), 4796. (* Equal Corresponding authors).
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Work Experience
- Associate Professor, Indian Institute of Technology, Gandhinagar (Feb 2020 to Present)
- Assistant Professor, Indian Institute of Technology, Gandhinagar (Jan 2013 to Feb 2020)
- Postdoctoral Fellow, Dana Farber Cancer Institute, Harvard Medical School (Jan 2010 - Dec 2012)
- Visiting Scientist: Whitehead Institute, MIT (Jan 2010 - June 2011)
- Postdoctoral Fellow, Brigham and Women's Hospital, Harvard Medical School and Brandeis University (Oct 2007 - Dec 2009)
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Awards
- DST - Ramanujan Fellow (2013-2018)
- Prof. Swaminathan Endowment Prize
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Patents
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ATM Inhibitors pharmaceutical composition and process for preparing the same: Kirubakaran, Sivapriya; Ravi Srimadhavi, Shaik, Althaf and Sugata Barui: Indian Patent Office, Patent Application No.: 201821039653, Oct 19, 2018
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Kirubakaran, Sivapriya; Thiruvenkatam, Vijay; Hussain, Javeena; Purushothaman Gayathri and Bhoir, Siddhant, "Phosphate derivatives of Myo-Inositol as RAS inhibitors", Indian Patent Office, Patent Application No.: 201721020827, Jun. 14, 2017
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Pharmaceutical composition and process for preparing the same: Kirubakaran, Sivapriya; Thiruvenkatam, Vijay; Juvale, Kapil; Singh, Vijay; Purushothaman, Gayathri and Shaik, Althaf, Indian - Patent Office, Patent Application No.: 201621024723, Jul. 19, 2016
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Substituted 1,2-Dihydro- 3H-Pyrazolo[4,3-C]Quinolin- 3- One as ATR Kinase Inhibitors: Kirubakaran, Sivapriya; Thiruvenkatam,Vijay; Shaik, Althaf and Bhakuni, Rashmi, Indian Patent Office, Patent Application No.: 201621026397, Aug. 2, 2016
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Novel compounds for treating H pylori infection and related gastric cancer: Pharmaceutical composition and process for preparing the same: Kirubakaran Sivapriya; Thiruvenkatam, Vijay; Juvale, Kapil; Singh, Vijay; Purushothaman, Gayathri and Shaik, Althaf"Indian Patent Office, Patent Application No.: 201621024723, Jul. 19, 2016
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COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTRO INTESTINAL & MICROBIAL INFECTIONS: United States application or PCT international application number 14/571,673, Date of publication: 16/12/2014. Inventors: Sivapriya Kirubakaran* & Lizbeth Hedstrom, Deviprasad Gollapalli, Greg Cuny, Suresh Gorla, Jihan Khan
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Compounds for treating mammalian gastrointestinal microbial infections, European Patent Application EP2408753, Lizbeth K Hedstrom, Gregory D Cuny, Deviprasad R Gollapalli, Sivapriya Kirubakaran, Boris Striepen, Suresh Kumar Gorla, Sushil K Maurya, Corey Robert Johnson, Mandapati Kavitha, Jihan Khan, Publication date: 25/1/2012
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