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Sivapriya Kirubakaran

  1. Faculty
  2. Chemistry

  3. Sivapriya Kirubakaran

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Sivapriya Kirubakaran

Kankuben Bakshirambhai Gelot Chair Professor, Chemistry

  • BSc: The Ethiraj college for women, 1999
  • MSc: University of Madras, 2001
  • PhD: IISc Bangalore, 2007

Email: priyak -AT- iitgn.ac.in

Website : http://labs.iitgn.ac.in/ccbl/

Office: 4/401 B
VOIP: 2450


  • Selected Publications

    1. Juvale, K.*; Purushothaman, G.*; Singh, V.; Shaik, A.; Ravi, S.;Thiruvenkatam, V.; Kirubakaran, S., Identification of selective inhibitors of Helicobacter pylori IMPDH as a targeted therapy for the infectionScientific Reports, 2019 9:190. DOI: 10.1038/s41598-018-37490-x (* Equal first authors).

    2. Bhakuni, R.; Shaik, A.; Kirubakaran, S., Evaluation of MBP tagged-hATR kinase domain catalytic activity with p53 Ser-15 phosphorylation. Biochemistry, 2018, 57, 47, 6592-6603.

    3. Shaik, A.; Bhakuni, R.; Kirubakaran, S., Design, Synthesis, and Docking Studies of New Torin2 Analogs as Potential ATR/mTOR Kinase Inhibitors. Molecules 2018, 23 (5), 992.

    4. Bhoir, S.; Shaik, A.; Thiruvenkatam, V. *; Kirubakaran, S. *, High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer. Scientific Reports 2018, 8 (1), 4796. (* Equal Corresponding authors).

  • Work Experience

    • Professor, Indian Institute of Technology Gandhinagar (Nov 2024 to Present)
    • Associate Professor, Indian Institute of Technology Gandhinagar (Feb 2020 - Nov 2024)
    • Assistant Professor, Indian Institute of Technology Gandhinagar (Jan 2013 - Feb 2020)
    • Postdoctoral Fellow, Dana Farber Cancer Institute, Harvard Medical School (Jan 2010 - Dec 2012)
    • Visiting Scientist: Whitehead Institute, MIT (Jan 2010 - June 2011)
    • Postdoctoral Fellow, Brigham and Women's Hospital, Harvard Medical School and Brandeis University (Oct 2007 - Dec 2009)

  • Awards

    • DST - Ramanujan Fellow (2013-2018)
    • Prof. Swaminathan Endowment Prize

  • Patents

    • ATM Inhibitors pharmaceutical composition and process for preparing the same: Kirubakaran, Sivapriya; Ravi Srimadhavi, Shaik, Althaf and Sugata Barui: Indian Patent Office, Patent Application No.: 201821039653, Oct 19, 2018

    • Kirubakaran, Sivapriya; Thiruvenkatam, Vijay; Hussain, Javeena; Purushothaman Gayathri and Bhoir, Siddhant, "Phosphate derivatives of Myo-Inositol as RAS inhibitors", Indian Patent Office, Patent Application No.: 201721020827, Jun. 14, 2017

    • Pharmaceutical composition and process for preparing the same: Kirubakaran, Sivapriya; Thiruvenkatam, Vijay; Juvale, Kapil; Singh, Vijay; Purushothaman, Gayathri and Shaik, Althaf, Indian - Patent Office, Patent Application No.: 201621024723, Jul. 19, 2016

    • Substituted 1,2-Dihydro- 3H-Pyrazolo[4,3-C]Quinolin- 3- One as ATR Kinase Inhibitors: Kirubakaran, Sivapriya; Thiruvenkatam,Vijay; Shaik, Althaf and Bhakuni, Rashmi, Indian Patent Office, Patent Application No.: 201621026397, Aug. 2, 2016

    • Novel compounds for treating H pylori infection and related gastric cancer: Pharmaceutical composition and process for preparing the same: Kirubakaran Sivapriya; Thiruvenkatam, Vijay; Juvale, Kapil; Singh, Vijay; Purushothaman, Gayathri and Shaik, Althaf"Indian Patent Office, Patent Application No.: 201621024723, Jul. 19, 2016

    • COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTRO INTESTINAL & MICROBIAL INFECTIONS: United States application or PCT international application number 14/571,673, Date of publication: 16/12/2014. Inventors: Sivapriya Kirubakaran* & Lizbeth Hedstrom, Deviprasad Gollapalli, Greg Cuny, Suresh Gorla, Jihan Khan

    • Compounds for treating mammalian gastrointestinal microbial infections, European Patent Application EP2408753, Lizbeth K Hedstrom, Gregory D Cuny, Deviprasad R Gollapalli, Sivapriya Kirubakaran, Boris Striepen, Suresh Kumar Gorla, Sushil K Maurya, Corey Robert Johnson, Mandapati Kavitha, Jihan Khan, Publication date: 25/1/2012

Research Interests

  • ● Drug discovery and cancer chemical biology
  • ● Use of small molecules to study cancer related proteins
  • ● Basic synthetic organic chemistry

Complete List of Publications