• Structural biology of macromolecular complexes
• Chemical Crystallography
• Insitu cryo-crystallizations of liquids
• Projects: a) Structural investigation of Alzheimer disease related protein gamma secretase activating protein (GSAP) b) Structural investigation of (Ataxia telangiectasia and Rad3-related protein) ATR and (Ataxia telangiectasia mutated) ATM Kinase protein

• Phosphate derivatives of Myo-Inositol as RAS inhibitors", Kirubakaran, Sivapriya; Thiruvenkatam, Vijay; Hussain, Javeena; Purushotaman Gayathri and Bhoir,Siddhant, Indian Patent Office, Patent Application No.:201721020827, Jun. 14, 2017.
• Pharmaceutical composition and process for preparing the same: Kirubakaran, Sivapriya; Thiruvenkatam, Vijay; Juvale, Kapil; Singh, Vijay; Purushothaman, Gayathri and Shaik, Althaf, Indian Patent Office, Patent Application No.: 201621024723, Jul. 19, 2016.
• Substituted 1,2-Dihydro- 3H-Pyrazolo[4,3-C]Quinolin- 3- One as ATR Kinase Inhibitors: Kirubakaran, Sivapriya; Thiruvenkatam, Vijay; Shaik, Althaf and Bhakuni, Rashmi, Indian Patent Office, Patent Application No.: 201621026397, Aug. 2, 2016.

• Assistant Research Professor, Indian Institute of Technology Gandhinagar (Jan 2013 to present)
• Postdoctoral Researcher, Beth Israel Deaconess Medical School/Harvard Medical School(June 2011 - Dec 2012)
• Postdoctoral Researcher, BU/DFCI/Harvard Medical School (Sep 2009 - May 2011)

Corresponding Author: * & #

• Identification of selective inhibitors of Helicobacter pylori IMPDH as a targeted therapy for the infection; Kapil Juvale^1,4,#, Gayathri Purushothaman^2,#, Vijay Singh², Althaf Shaik¹, Srimadhavi Ravi¹, Vijay Thiruvenkatam^2,3, Sivapriya Kirubakaran^1,2* Scientific Reports, 2018 (Accepted) (IF 4.12)
• Exploring solvated dimer of Gefitinib: A quantitative analysis Deekshi Angira, Althaf Shaik, Sivapriya Kirubakaran and Vijay Thiruvenkatam^*, Acta Crystallographica Section C: Structural Chemistry, C74, 944-950, 2018 (IF 8.67)
• A quantitative and qualitative analysis of intermolecular interactions in substituted xanthenedione derivatives; Gayathri Purushothaman and Vijay Thiruvenkatam^*, Acta Crystallographica Section C: Structural Chemistry, 74, 7, 2018 (IF 8.67)
• High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer; Siddhant Bhoir, Vijay Thiruvenkatam^#, Sivapriya Kirubakaran*, Scientific Reports, 8 (1), 4796, 2018 (IF 4.12)
• Design, synthesis, and biological evaluation of Helicobacter pylori inosine 5’monophosphate dehydrogenase (HpIMPDH) inhibitors Niteshkumar U. Sahu¹, Gayathri Purushothaman², Vijay Thiruvenkatam^2,3, Prashant S. Kharkar1 Drug Development Research, 1–8, 2018 (IF 2.646)
• Role of =NOH intermolecular interactions in oxime derivatives via Crystal structure, Hirshfeld surface, PIXELC and DFT calculations, Gayathri Purushothaman, Vijay Thiruvenkatam; Journal of Molecular Structure; 1148, 371-380, 2017 (IF 2.01)

Complete List of Publications